Systems Biology and Computational Proteomics

Systems Biology and Computational Proteomics

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The RECOMB Satellite Conferences on Systems Biology and Computational Proteomics were held December 1 3, 2006, at La Jolla, California. The S- tems Biology meeting brought researchers together on various aspects of s- tems biology, including integration of genome-wide microarray, proteomic, and metabolomic data, inference and comparison of biological networks, and model testing through design of experiments. Speci?c topics included: Pathway mapping and evolution in protein interaction networks Inference of protein signaling networks for understanding cellular responses and developmental programs Model prediction of drug mechanism of action and toxicity Multi-scale methods which bridge abstract and detailed models Systematic design of genome-scale experiments Modeling and recognition of regulatory elements Identi?cation and modeling of cis-regulatory regions Modeling the structure and function of regulatory regions Comparative genomics of regulation Withthesequencingofthegenome, andsubsequentidenti?cationoftheparts list (the gene and their protein products), there is a renewed emphasis on stu- ing the proteome. This year, the computational proteomics meeting focused on on computational mass spectrometry. Mass spectrometry is emerging as a key technology for proteomics. The last few years have seen tremendous impro- ment in the quality and quantity of available peptide mass spectrometry data, as well asthe realizationthat advanced computational approachesarecritical to thesuccessofthis technology. Theconferenceexploredtheuseofthis technology in various proteomic applications, including, but not limited to: protein ident- cation and quanti?cation in speci?c cellular environments; structural genomics; networks of protein interaction; post-translational modi?cations; and others. We received approximately 50 full paper submissions to the joint workshops.qRoded Sharan Tel Aviv University Alfonso Valencia Centro Nacional de ... Chen University of Southern California Eric Davidson California Institute of Technology Nathan Edwards University of Maryland Keith Elliston ... Bernhard Palsson University of California, San Diego Dana Pea#39;er Harvard Medical School Pavel Pevzner University of California, San ... University Knut Reinert Freie Universit I┬łat Berlin Cenk Sahinalp Simon Fraser University Ron Shamir Tel Aviv University Avg. Rankanbsp;...

Title:Systems Biology and Computational Proteomics
Author: Trey Ideker, Vineet Bafna
Publisher:Springer Science & Business Media - 2007-07-20

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